This work adds to the responses from different angles, try to unravel the mystery of human existence: What is man? Anthropology, in its various branches, provides materials to get closer to that reality, which escapes Hondón human research because there is always a plus, which is only possible interpretative key, according to the author, considering man in his dimension deeper and more mysterious in their relationship with God the Creator and Savior. At the theological level lies the work of Dr. Ponce Cuellar, the mystery of man, who studies the dawn of human existence, whose basic-creation, call of God in Christ and original sin make up the life and being of man. The author of the book each structure in a three-chapter: first, a comprehensive and set the theme of Holy Scripture, according to current research, still later, with the same scientific rigor, an overview of the history of Tradition and the Magisterium on this problem, and finishes in third place, with a profound reflection in the light of the positive data and the current theology, presenting various solutions to assume that the author believes that more adjusted to the texts of Scripture and magisterial, and more significance for man. The theme of the book is certainly present in each of its parts. The issue of creating situational relevance today acquired by the awareness of the dangers of unlimited exploitation of nature and its energies, the negative experiences of hypertrophied technique, a menace on its use against the dignity of the person, and also by the fear of atomic annihilation. But the theologian who must at all times be aware of the fundamental importance of the dogma of creation, not to rely solely on circumstantial reasons for the study of this dogma, making an appeal passenger. Only a broad and deep of creation can give to man the knowledge and strength needed to master the situation in time to remedy your needs.