The factory of unhappiness as reality, nothing virtual, of a social body hyper-exploited, stressed, reduced by the warmongering strategy adopted by world powers today. The events punctuated, in a privileged way, by the crisis of the new digital economy from the spring of 2011, the attacks of September 11 and the war in Iraq have as a common element the breaking of the promise of "happiness" ( interesting and creative jobs, expectation of immediate profits, stock market euphoria) that had been offered to knowledge workers, the driving force of the last cycle of economic growth. On the contrary, the crisis reveals a reality marked by new forms of neurosis: panic, as a subjective collapse in the face of the hyperstimulation contained in digital work and in life in big cities; depression, neuronal anesthesia, in the face of the crisis of meaning derived from the prolongation of situations subjected to extremely high stress. The crisis describes itself as a crisis of subjectivity, a psychic crisis as well as a social and economic one. In Bifo's own words: "This book aims to point out and map a new disciplinary field that is found at the intersection of economics, communication technology and psychochemistry. A mapping of this new disciplinary field is essential if we want to describe and understand the production process of capital and the production of social subjectivity in the era that follows mechanical industrial modernity and, therefore, if we want to elaborate strategies of subtraction".