Elsa Leticia García Argüelles was born in Xalapa, Veracruz, in 1968. She earned her undergraduate degree from the Universidad Veracruzana. She holds a Master's degree in Latin American Literature from New Mexico State University. In 2005, she completed her doctoral studies in Ibero-American Literature at the Faculty of Philosophy and Letters of the National Autonomous University of Mexico (UNAM).

She is currently a professor and researcher in the Doctoral Programs in Humanities and Arts and in New Spain Studies at the Autonomous University of Zacatecas. She is a member of the National System of Researchers.

Her main line of research focuses on women's literature and the woman as heroine in narrative. She has studied this topic from the perspective of femininity, its mentality, the body, and the reflections that arise around stereotypes, violence, and inequality as seen through its artistic representation in literature. Other topics covered in her work include colonial Mexican literature, 19th-century Mexican literature, contemporary Latin American literature, and Chicano literature. She has also studied the work of Jorge Ibargüengoitia, Mario Bellatín, María Luisa Puga, Sandra Cisneros, Cristina Peri Rossi, and Cristina Rivera Garza, among others.