This book is a collaborative work resulting from an international effort between UNAM (Mexico) and UASB (Ecuador). Drawing on the link between critical perspectives in geography and public health, it characterizes the territorial crisis after four decades of neoliberalism. Its counter-hegemonic proposal positions itself at the heart of the contradiction and struggle against the dynamics of the Latin American territorial order, defined by self-destructive spaces of capital and the multiple emergence of territories of resistance. The book is structured in four sections. The first two characterize the territorial crisis, the forces that trigger it, and the role of critical science in this process. The other two demonstrate the destructive consequences of this crisis on healthy living and the environment, as well as the plurality of political struggles resisting its advance.