The systematic accelerations of late capitalism and the rapid advances in our knowledge of living systems, their genetic and algorithmic codes, have blurred the limits of the human, and have called into question the classic object of study of the Humanities. Along with this decline in anthropocentrism, the great acceleration of climate change and the advent of the sixth mass extinction generate a new configuration of nature. The end of Man is already a reality, and therefore the demand is imposed in our days to understand what lies beyond, what comes after. In Posthuman Knowledge, Rosi Braidotti analyzes in detail the profound impact of these revolutions in three areas: the constitution of emerging subjectivities, scientific production, and the practice of academic humanities. Drawing on the most recent research in feminist, postcolonial and anti-racist theory, Braidotti argues that the human was never a neutral category, but was always linked to power and privilege. Therefore, going beyond the old schemes with which Man defined himself today becomes not only a necessity, but also an ethical requirement. Posthuman knowledge is, above all, a critical calling: the project of reconfiguring knowledge and experience, overthrowing anthropocentrism, and critically analyzing the discriminatory logic of humanism. An invitation to think boldly and creatively about everything we are in the process of becoming.